个人简介
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李杰，女，1984年09月生，博士，硕士研究生导师，湖北医药学院附属太和医院检验科副主任；湖北省免疫学会第十一届理事会理事；湖北省医学会检验医学分会青年委员；湖北省医学生物免疫学会基础专委会委员；湖北省免疫学会科普与教学专业委员会委员，《湖北医药学院学报》杂志青年编委。主要从事免疫学方向的研究工作。
主持完成科研项目6项，其中湖北省自然科学基金1项，湖北省教育厅2项。发表论文14篇，其中SCI收录论文11篇。
代表作：
1.Chang L, Li G, Jiang S,Li J, Yang J, Shah K, Zhou L, Song H, Deng L, Luo Z, Guo Y, Yan Y. 1-Pyrroline-5-carboxylate inhibit T cell glycolysis in prostate cancer microenvironment by SHP1/PKM2/LDHB axis. Cell Commun Signal. 2024 Feb 8;22(1):101. (IF 8.4)
2.Li L#, Gao M#, Li J#, Xie X#, Zhao H#, Wang Y#, Xu X, Zu S, Chen C, Wan D, Duan J, Wang J, Aliyari SR, Gold S, Zhang J, Qin CF, Shi PY, Yang H, Cheng G. Identification of an immunogenic epitope and protective antibody against the furin cleavage site of SARS-CoV-2. EBioMedicine. 2023 Jan;87:104401. (co-first author，IF 11.1)
3. Lili Li#, Meiling Gao#, Jie Li#, Shulong Zu#, Yanan Wang#， Chunfeng Chen, Dingyi Wan, Jing Duan, Roghiyh Aliyari, Jingfeng Wang, Jicai Zhang, Yujie Jin, Weijin Huang, Xiaoxia Jin, Minxin Shi, Youchun Wang, Cheng-Feng Qin, Heng Yang,* and Genhong Cheng*.Methods to Identify Immunogenic Peptides in SARS-CoV-2 Spike and Protective Monoclonal Antibodiesin COVID-19 Patients. Small Methods. Small Methods 2021 Jul 15;5(7):2100058. (co-first author，IF 14.188)
4.Lili Li 1,2#, Jie Li 3#, Meiling Gao1,2,3#, Huimin Fan1,2#, Yanan Wang4#, Xin Xu1,2,Chunfeng Chen4, Junxiao Liu 1,2, Jocelyn Kim5, Roghiyh Aliyari 5, Jicai Zhang3, Yujie Jin 3,Xiaorong Li 1,2, Feng Ma1,2, Minxin Shi6, Genhong Cheng5*‡ and Heng Yang1,2*‡, Interleukin-8 as a Biomarker for Disease Prognosis of Coronavirus Disease-2019 Patients. Front Immunol. 2021 Jan 8;11:602395. (co-first author，IF 7.561)
5.Shulong Zu#, Yong-Qiang Deng#, Chao Zhou#,Jie Li#, Lili Li 1 2, Qi Chen 3, Xiao-Feng Li 3, Hui Zhao 3, Sarah Gold 5, Jun He 6, Xiang Li 7, Changqing Zhang 8, Heng Yang 9 10, Genhong Cheng 11, Cheng-Feng Qin. 25-Hydroxycholesterol is a potent SARS-CoV-2 inhibitor. Cell Res. 2020 Aug 18;1-3. (co-first author，IF 25.611)
6.Li J#, Song S#, Li X3, Zhu J4,5, Li W6, Du B4, Guo Y7, Xi X7, Han R7,8,9. Down-regulation of FGF2 contributes to the premature senescence of mouse embryonic fibroblast. Med Sci Monit. 2020 Mar 19;26:e920520. (IF 2.640)
7.李杰，李转转，张吉才*.十堰地区女性人群亚甲基四氢叶酸还原酶基因多态性分析.中华医学遗传学杂志.2018，35（4）：580-584
8.李杰,李海平,李转转,靳玉洁,张吉才*.CCR9/CCL25 途径在小鼠皮肤移植急性排斥反应中的表达及意义.中华器官移植杂志. 2016，37(2):106-111.
9.Li J, Xiong T, Xiao R, Xiong A, Chen J, Altaf E, Zheng Y, Zhu G, He Y, Tan J*. Anti-CCL25 antibody prolongs skin allograft survival by blocking CCR9 expression and impairing splenic T-cell function. Arch Immunol Ther Exp (Warsz) ,2013 Jun;61(3):237-44. (IF 4.292)
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